ACTILYSE CATHFLO is a medication specifically designed for use in the medical field to restore the function of central venous access devices (CVADs) that have become occluded. It contains the active ingredient alteplase, which is a type of tissue plasminogen activator (tPA). This enzyme plays a crucial role in the breakdown of blood clots, effectively dissolving them to reopen the blocked catheters. ACTILYSE CATHFLO works by targeting the fibrin matrix of the clot, promoting its degradation and thereby restoring proper flow through the catheter. It is commonly used in hospital settings and clinics where patients require long-term intravenous treatments, ensuring that their access lines remain open and functional for the delivery of medications, fluids, and nutritional support.