Entresto is a prescription medication primarily used in the treatment of heart failure, specifically for patients with chronic heart failure to reduce the risk of cardiovascular death and hospitalization. It is a combination drug that contains two active ingredients: sacubitril, which is a neprilysin inhibitor, and valsartan, an angiotensin receptor blocker (ARB). Sacubitril helps to increase the levels of protective natriuretic peptides in the body, while valsartan blocks the action of angiotensin II, a substance that narrows blood vessels. Together, these actions help to relax blood vessels, making it easier for the heart to pump blood and improve its function. Entresto is typically prescribed when other heart failure medications are not sufficiently effective, and it is available in tablet form to be taken orally.
When using ENTRESTO, it's crucial to adhere strictly to your doctor's instructions and thoroughly read the label that accompanies the medication. ENTRESTO can cause side effects that may impair your ability to drive or operate machinery safely. Common side effects include dizziness, cough, and high potassium levels, which could lead to feelings of faintness or weakness. Rare but serious side effects, such as angioedema (swelling under the skin), require immediate medical attention. It's also essential to inform your doctor about all other medications you're taking, as ENTRESTO can interact with them in ways that might necessitate adjustments to your treatment plan. Always prioritize safety and open communication with your healthcare provider to ensure the best outcomes while using ENTRESTO.