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Insulin Comb 25, commonly known as Insuman Comb 25, is a premixed insulin medication designed for the treatment of diabetes mellitus. It is a combination of intermediate-acting and fast-acting insulin, typically comprising 25% soluble insulin for rapid action and 75% isophane insulin for prolonged effect. This blend helps in managing both basal and postprandial blood glucose levels. Insuman Comb 25 is administered subcutaneously and is often used in a regimen that involves injections twice a day, usually before breakfast and dinner. The precise dosage and timing are tailored to the individual's needs, based on their blood glucose monitoring, lifestyle, and dietary intake. It is crucial for patients to follow their healthcare provider's instructions closely when using this medication to effectively manage their diabetes and minimize the risk of side effects.