Insulin Comb 50, marketed under the brand name InsuMan Comb 50, is a pre-mixed insulin medication designed for the treatment of diabetes mellitus. It is a combination of intermediate-acting insulin and fast-acting insulin, typically comprising 50% soluble insulin (fast-acting) and 50% isophane insulin (intermediate-acting). This blend is engineered to provide both rapid onset of action to manage blood glucose levels after meals and sustained action to maintain stable blood glucose levels throughout the day and night. InsuMan Comb 50 is administered subcutaneously and is often used in a regimen that includes diet, exercise, and regular blood sugar monitoring. It is suitable for adults and children with diabetes when insulin therapy is necessary to control their blood glucose levels.