INTELENCE, with its active ingredient etravirine, is a prescription medication used in the treatment of human immunodeficiency virus (HIV) infection. It belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs), which work by blocking the reverse transcriptase enzyme. This enzyme is crucial for the replication of HIV, and by inhibiting it, INTELENCE helps to lower the amount of HIV in the body. Although INTELENCE does not cure HIV or AIDS, it can significantly reduce the risk of HIV-related complications and improve the quality of life for those living with the virus. It is typically used in combination with other antiretroviral medications as part of an antiretroviral therapy regimen.