Kineret, also known by its generic name anakinra, is a biologic medication primarily used in the treatment of rheumatoid arthritis (RA) and neonatal-onset multisystem inflammatory disease (NOMID), a form of cryopyrin-associated periodic syndromes (CAPS). It functions as an interleukin-1 receptor antagonist, effectively blocking the activity of interleukin-1, a protein in the body that plays a key role in causing inflammation and joint damage in individuals with rheumatoid arthritis. By doing so, Kineret helps to reduce the symptoms associated with these conditions, such as pain and swelling in the joints, and can improve physical function. It is administered through subcutaneous injection and is often considered for use when other treatments have not been effective. Like all medications, Kineret can have side effects, and its use should be closely monitored by a healthcare provider.