Lokelma, whose generic name is sodium zirconium cyclosilicate, is a medication primarily used in the treatment of hyperkalemia, a condition characterized by elevated levels of potassium in the blood. Hyperkalemia can lead to serious health issues, including heart rhythm problems. Lokelma works by binding to potassium ions in the gastrointestinal tract, which helps to reduce the overall potassium levels in the body. It is administered orally and is known for its ability to act quickly, making it an effective option for managing acute episodes of hyperkalemia as well as for long-term maintenance in patients with chronic conditions that predispose them to high potassium levels.