Methofill is a medication primarily used in the treatment of various autoimmune diseases, including rheumatoid arthritis, psoriasis, and certain forms of juvenile idiopathic arthritis. It contains methotrexate as its active ingredient, which belongs to a class of drugs known as disease-modifying antirheumatic drugs (DMARDs). Methofill works by inhibiting the activity of an enzyme involved in the rapid growth of cells, which helps to reduce inflammation and slow down the progression of the disease. It is available in different forms, including tablets and injectables, allowing for flexibility in administration based on the patient's needs and the severity of the condition. As with any medication, it is important to use Methofill under the guidance of a healthcare professional to manage dosages and monitor for potential side effects.