Moduretic is a combination medication that is used primarily to treat high blood pressure (hypertension) and to reduce excess fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This medication combines two active ingredients: amiloride, which is a potassium-sparing diuretic, and hydrochlorothiazide, which is a thiazide diuretic. Together, these components work by increasing the amount of urine produced, helping the body to get rid of extra salt and water while also preventing the potassium levels from dropping too low. By managing fluid levels and blood pressure, Moduretic can help reduce the risk of strokes, heart attacks, and kidney problems. It is important to use this medication under the guidance of a healthcare professional, as it requires monitoring for potential side effects and interactions with other medications.