MULPLEO, also known by its generic name, Luspatercept-aamt, is a prescription medication designed for the treatment of certain types of anemia. Specifically, it is approved for use in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions, and for those with myelodysplastic syndromes (MDS) who have anemia that has not responded well to other treatments. MULPLEO works by helping the body produce more red blood cells, thereby reducing the need for transfusions. It is administered through subcutaneous injection and is part of a class of drugs known as erythroid maturation agents. As with any medication, it is important to use MULPLEO under the guidance of a healthcare professional, who can provide information on dosage, potential side effects, and other relevant considerations.