Nardil is a brand name for the medication phenelzine, which belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs). It is primarily used in the treatment of depression, particularly when other treatments have not been effective. Nardil works by inhibiting the action of an enzyme called monoamine oxidase, which is involved in breaking down neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By decreasing the breakdown of these chemicals, Nardil helps increase their levels, thereby enhancing mood and alleviating symptoms of depression. Due to potential interactions with certain foods and other medications, it requires careful dietary and medication management to avoid serious side effects.