NATRILIX SR is a sustained-release medication primarily used in the management of hypertension, also known as high blood pressure. The active ingredient in NATRILIX SR is indapamide, which belongs to a class of medications known as diuretics, specifically a thiazide-like diuretic. It works by increasing the excretion of sodium and chloride in the kidneys, which helps to lower blood pressure by reducing the overall volume of fluid in the blood vessels. The "SR" in its name stands for "sustained release," meaning that the drug is formulated to release the active ingredient gradually over time to provide a more consistent therapeutic effect. This feature allows for once-daily dosing, which can improve patient compliance with the treatment regimen. NATRILIX SR is often prescribed when other blood pressure medications have not been effective or as part of a combination therapy for better blood pressure control.