Neotigason, known generically as Acitretin, is a systemic retinoid medication primarily used in the treatment of severe psoriasis and other disorders of keratinization. It works by modulating the growth and differentiation of skin cells, effectively reducing the symptoms of these conditions. As an oral medication, Neotigason is often prescribed when topical treatments and light therapy are not effective. It is a potent drug with a range of potential side effects, including teratogenic effects, hence it is not recommended for use by pregnant women or those planning to become pregnant. Patients on Neotigason require careful monitoring by their healthcare provider to manage any adverse effects and to ensure the treatment's efficacy.