Novofem is a hormone replacement therapy (HRT) medication primarily used to alleviate symptoms associated with menopause in women, such as hot flashes, night sweats, mood swings, and vaginal dryness. It contains two active ingredients: estradiol (a form of estrogen) and norethisterone acetate (a form of progestogen). Estradiol works by replacing the estrogen that the body no longer produces after menopause, while norethisterone acetate is added to protect the uterus lining from the potential harmful effects of estrogen alone. Novofem is typically prescribed to women who have not had a hysterectomy and are experiencing troublesome menopausal symptoms. It is available in the form of tablets that are taken orally, usually following a specific cycle or regimen as directed by a healthcare provider.