Protopic, generically known as tacrolimus, is a topical medication primarily used in the treatment of moderate to severe atopic dermatitis (eczema) when other treatments have not been effective. It belongs to a class of drugs known as topical calcineurin inhibitors, which work by suppressing the immune system to decrease inflammation and relieve the itchiness associated with eczema. Protopic is available in the form of an ointment and is applied directly to the affected skin areas. It is suitable for short-term and intermittent long-term therapy, offering an alternative to traditional steroid-based treatments, thereby reducing the risk of potential side effects associated with prolonged steroid use. However, it is important to use Protopic under the guidance of a healthcare professional, as it carries warnings for potential risks of skin cancer and lymphoma.