Repatha, also known by its generic name evolocumab, is a prescription medication used to lower high levels of cholesterol in the blood. It belongs to a class of drugs known as PCSK9 inhibitors, which work by blocking a specific protein that affects the liver's ability to remove LDL cholesterol, often referred to as "bad" cholesterol, from the blood. By inhibiting this protein, Repatha helps to reduce the amount of LDL cholesterol circulating in the bloodstream. It is commonly prescribed for individuals who have not been able to lower their cholesterol levels sufficiently through diet and statin therapy, and it is particularly beneficial for patients with familial hypercholesterolemia, a genetic condition that results in very high levels of cholesterol, or those who have established cardiovascular disease. Repatha is administered through subcutaneous injection and is often used in combination with other cholesterol-lowering treatments to achieve optimal results.