Rifinah 150 is a combination medication primarily used in the treatment and prevention of tuberculosis (TB), an infectious disease caused mainly by the bacterium Mycobacterium tuberculosis. This medication combines two active ingredients: rifampicin (also known as rifampin in some regions) at a dose of 150 mg and isoniazid. Rifampicin works by inhibiting the DNA-dependent RNA polymerase in bacterial cells, preventing them from making essential proteins, leading to their death. Isoniazid, on the other hand, interferes with the synthesis of mycolic acid, a crucial component of the bacterial cell wall. Together, these drugs provide a potent therapy against TB, helping to prevent the spread of the disease and reduce the risk of drug resistance when taken as prescribed. It is important for patients to follow their healthcare provider's instructions closely when taking Rifinah 150 to ensure the best possible outcomes.