SAMSCA, generically known as tolvaptan, is a prescription medication that belongs to a class of drugs known as vasopressin V2-receptor antagonists. It is specifically designed to treat low sodium levels (hyponatremia) in the blood, a condition that can occur in patients with heart failure, liver disease, and certain hormonal imbalances. By blocking the action of the hormone vasopressin, SAMSCA helps to increase the excretion of water through the urine without causing the loss of sodium, thereby raising sodium levels in the blood. It is administered orally in tablet form. As with any medication, it is important to use SAMSCA under the guidance of a healthcare professional, as it can have potential side effects and may not be suitable for all patients.