Selincro, generically known as nalmefene, is a medication primarily used in the treatment of alcohol dependence. It functions as an opioid receptor antagonist, specifically targeting the brain's reward pathways that are stimulated by alcohol consumption. By blocking these opioid receptors, Selincro reduces the pleasurable effects associated with drinking alcohol, thereby helping individuals to decrease their alcohol intake. It is typically prescribed as part of a comprehensive treatment plan that includes psychological support, aimed at adults who have a high level of alcohol dependence and who continue to have a significant level of alcohol consumption. Selincro is taken orally and is recommended for use on an as-needed basis, meaning it should be taken on days when the individual feels at risk of drinking. This medication offers a targeted approach to managing alcohol dependence, providing a pharmacological tool to support individuals in reducing their alcohol consumption.