SIMBRINZA is a prescription eye drop medication primarily used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is a combination of two active ingredients: brinzolamide, a carbonic anhydrase inhibitor, and brimonidine tartrate, an alpha-2 adrenergic receptor agonist. This dual-action formula works by reducing the production of aqueous humor (the fluid in the eye) and enhancing fluid drainage, which in turn helps to decrease pressure within the eye. SIMBRINZA is typically recommended for patients who require more than one type of medication for effective IOP management, offering the convenience of fewer drops without the use of beta-blockers. As with any medication, it is important to use SIMBRINZA under the guidance of a healthcare professional to ensure its safe and effective use.