Typherix is a vaccine used to prevent typhoid fever, a serious disease caused by the bacterium Salmonella typhi. Typhoid fever is primarily spread through contaminated food and water and is more prevalent in areas with poor sanitation. The Typherix vaccine works by stimulating the body's immune system to produce antibodies against the Salmonella typhi bacteria, providing immunity to individuals who are vaccinated. It is commonly recommended for travelers to regions where typhoid fever is endemic, as well as for people living in areas with high rates of the disease. The vaccine is administered via injection and is known for its effectiveness in preventing typhoid fever, contributing significantly to public health efforts in controlling the spread of this potentially life-threatening illness.