XOFLUZA, also known by its generic name baloxavir marboxil, is an antiviral medication designed to treat influenza (flu). Approved by the FDA, XOFLUZA works by inhibiting the cap-dependent endonuclease activity of the influenza virus, which is essential for viral replication. This mechanism of action helps to reduce the duration of flu symptoms and potentially prevents the spread of the virus to others. XOFLUZA is available in tablet form and is prescribed for the treatment of acute, uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. Its single-dose regimen offers a convenient treatment option compared to other antiviral medications that require multiple doses over several days.