Yentreve, known generically as duloxetine, is a medication primarily used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. It belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs), which work by increasing the levels of serotonin and norepinephrine, neurotransmitters that help regulate mood and pain perception in the brain. Yentreve is available in capsule form and is taken orally. It is important for patients to follow their healthcare provider's instructions closely when taking Yentreve, as it can have side effects and may interact with other medications.